RABIES, a virulent disease, developed primarily in | ably in intensity and in the character of its symptoms in and peculiar to the canine species. Its occurrence in the different species of creatures. Pasteur has shown that, if same manner in other carnivorous animals, as the fox, it is transmitted from the diseased dog to the monkey wolf, hyæna, jackal, raccoon, badger, and skunk, has been and ultimately from monkey to monkey, at each transasserted; but there is every probability that it is originally mission it becomes more attenuated in virulence, and a disease of the dog. It is communicated by inoculation remains so attenuated when passed again to the dog, to nearly all, if not all, warm-blooded creatures. The trans-rabbit, or guinea-pig, nor will it any longer produce the mission from one animal to another only certainly takes disease in dogs by hypodermic inoculations. Even inocuplace through inoculation with viruliferous matters. The lation by trepanning the cranium, which is so infallible in malady is generally characterized at a certain stage by an conveying rabies, may produce no result, the dog thenceirrepressible desire in the animal to act offensively with forward being protected, and no longer capable of receiving its natural weapons, dogs and other carnivora attacking the disease. On the other hand, the rabific virus is inwith their teeth, herbivora with their hoofs or horns, and tensified when passed from rabbit to rabbit, or from birds with their beaks, when excited ever so slightly. In guinea-pig to guinea-pig; and after several transmissions the absence of excitement the malady may run its course through the bodies of these animals it regains the maxiwithout any fit of fury or madness. Transmission of the mum virulence which it possessed before it was enfeebled disease to man produces HYDROPHOBIA (q.v.) or dread of by being passed through the monkey. And the same thing water, but in animals this symptom is rarely, if ever, holds with respect to the virulence of the ordinary rabid observed. Rabies has been known from the very earliest dog when virus which is far from having reached its times, and serious outbreaks have been recorded as occurmaximum intensity is conveyed to the rabbit, it requires ring among dogs, wolves, and foxes in different parts of to be passed through several of these animals before it the world, particularly in western Europe and in North reaches its maximum. It may be mentioned that the and South America. It is very frequent in Europe and disease is not readily conveyed from man to animals, appears to be on the increase. France, Germany, upper either accidentally or experimentally. The virus appears Italy, and Holland evidently suffer more than other Con- to exist in greatest intensity in the salivary glands and tinental countries. England is becoming more frequently their secretion, in the brain and spinal cord, and perhaps visited than before, though Scotland and Ireland are much to a lesser degree in the blood; doubtless it exists also in less troubled than England. Spain is also sometimes other fluids and tissues of the diseased animal. The severely scourged by it; but it is rare in Portugal. On principal alterations found in the bodies of rabid animals the American continent it is well known, though on the after death are located in the spinal cord, especially its eastern side of the Andes it is rarely if ever seen; and it upper portion, the medulla oblongata, certain parts of has never been heard of in Quito. In the West Indies the brain, and the salivary glands, more particularly the -in Hispaniola, Jamaica, Domingo, Havana, Guadaloupe, submaxillary and sublingual,-less in the parotid. The and Hayti-as well as in Ceylon, it is frequently wit stomach, kidneys, and other organs also present alteranessed, and in 1813 it was introduced into Mauritius. It tions which are more or less significant, especially the exists in North and South China, and has been reported former, in which foreign bodies, as hair, wood, stones, in Cochin China and the kingdom of Anam. It is fre- earth, pieces of cloth, &c., are very frequently found. quent and fatal in India; and it is by no means rare in But the nature of the lesions, as well as the symptomatoSyria, Palestine, and Turkey. It has been observed in logy, shows that the action of the poison is more especially the Hijaz in Arabia, and in North Africa and Egypt. exerted on the brain or spinal cord, though the eighth Hydrophobia has been reported in Algeria; but Rohlfs pair of nerves, and branches of the fifth and seventh pairs, asserts that it is unknown in Morocco. Gibraltar and are not involved in animals, as in man. Malta have been seriously invaded at times, and in Sweden, Denmark, Norway, Russia, and Lapland it has been frequently seen in an epizootic form; but it is not yet positively decided whether it exists in the Arctic regions. Steller and Erman assert that it is unknown in Kamchatka and Greenland; but Hayes (The Open Polar Sea) gives us the particulars of an outbreak of disease in South Greenland, which persisted for several years, caused him the loss of his sledge-dogs in 1870, and in 1872 extended from Smith's Sound to Jakobshavn, threatening the utter extinction of the species, and with it the disappearance of the Eskimo. In most of its features it appeared to be rabies. The scourge is unknown, according to reliable evidence, in Australia and New Zealand, Tasmania, the Azores, and St Helena, as well as the island of Madeira; it has not been seen at Sumatra, nor in East, South, and West Africa, nor in the island of Réunion. Rabies (hydrophobia) is almost invariably fatal in man, and in the dog it nearly always terminates in death, though instances of recovery are recorded; and it is extremely probable that in those cases in which people have been bitten by dogs and subsequently perished from hydrophobia, without the animals themselves offering any marked indications of illness either at the time or afterwards, these have been suffering from a mild form of the disease. It is also fatal to horses, cows, pigs, goats, and cats, but not to fowls, many of these recovering from accidental or experimental inoculation. Indeed rabies varies consider The period in which the symptoms of the disease become manifest, especially after accidental inoculations, as bites, varies extremely; indeed there is no disease in which the period of latency or incubation is more variable or protracted, this being sometimes limited to a few days or weeks and extending in rare cases to more than twelve months. In experimental inoculations the period is greatly shortened and the results more certain, all the more so if the virus is introduced into the cranial cavity by trepanning, or into the blood-stream by intravenous inoculation. In accidental inoculations, as in wounds from rabid dogs, a certain but varying percentage escape. This immunity may be due to natural non-receptivity, to the wound not having been inflicted in a very vascular part, or to the saliva having been expended from frequent bites on other animals, or intercepted by clothing, hair, wool, &c. Symptoms.-The disease has been divided into three stages or periods, and has also been described as appearing in at least two forms, according to the peculiarities of the symptoms. But, as a rule, one period of the disease does not pass suddenly into another, the transition being almost imperceptible; and the forms do not differ essentially from each other, but appear merely to constitute animal, or other modifying circumstances. These forms have been varieties of the same disease, due to the natural disposition of the designated true or furious rabies (Fr. rage vrai; Germ. rasende Wuth) and dumb rabies (Fr. rage muc; Germ. stille Wuth). The malady does not commence with fury and madness, but in a strange and anomalous change in the habits of the dog: it becomes dull, gloomy, and taciturn, and seeks to isolate itself in out-of-theway places, retiring beneath chairs and to odd corners. its retirement it cannot rest: it is uneasy and fidgety, and no But in especially adhere to the upper surface of the tongue and to the sooner has it lain down than suddenly it jumps up in an agitated | tint, somewhat masked by patches of dust or earth, which more its master. There is no dread of water in the rabid dog; the animal is generally thirsty, and if water be offered will lap it with avidity, and swallow it at the commencement of the disease. And, when, at a later period, the constriction about the throat-symptomatic of the disease-renders swallowing difficult, the dog will none the less endeavour to drink, and the lappings are as frequent and prolonged when deglutition becomes impossible. So little dread has the rabid dog of water that it will ford streams and swim rivers; and when in the ferocious stage it will even do this in order to attack other creatures on the opposite side. The evidence on this head is overwhelming. At the commencement of the disease the dog does not usually refuse to eat, and some animals are voracious to an unusual degree. But in a short time it becomes fastidious, only eating what it usually has a special predilection for. Soon, however, this gives place to a most characteristic symptom-either the taste becomes extremely depraved or the dog has a fatal and imperious desire to bite and ingest everything. The litter of its kennel, wool from cushions, carpets, stockings, slippers, wood, grass, earth, stones, glass, horse-dung, even its own fæces and urine, or whatever else may come in its way, are devoured. On examination of the body of a dog which has died of rabies it is so common to find in the stomach a quantity of dissimilar and strange matters on which the teeth have been exercised that, if there was nothing known of the animal's history, there would be strong evidence of its having been affected with the disease. When a dog, then, is observed to gnaw and eat suchlike matters, though it exhibits no tendency to bite, it should be suspected. The mad dog does not usually foam at the mouth to any great extent at first. The mucus of the mouth is not much increased in quantity, but it soon becomes thicker, viscid, and glutinous, and adheres to the angles of the mouth, fauces, and teeth. It is at this period that the thirst is most ardent, and the dog sometimes furiously attempts to detach the saliva with its paws; and, if after a while it loses its balance in these attempts and tumbles over, there can no longer be any doubt as to the nature of the malady. There is another symptom connected with the mouth in that form of the disease named "dumb madness" which has frequently proved deceptive. The lower jaw drops in consequence of paralysis of its muscles, and the mouth remains open. The interior is dry from the air passing continually over it, and assumes a deep red The voice of the rabid dog is very peculiar, and so characteristic that to those acquainted with it nothing more is needed to prove the presence of the disease. Those who have heard it once or twice never forget its signification. Owing to the alterations taking place in the larynx the voice becomes hoarse, cracked, and stridulous, like that of a child affected with croup,—the “voix du coq," as the French have it. A preliminary bark is made in a somewhat elevated tone and with open mouth; this is immediately succeeded by five, six, or eight decreasing howls, emitted when the animal is sitting or standing, and always with the nose elevated, which seem to come from the depths of the throat, the jaws not coming together and closing the mouth during such emission, as in the healthy bark. This alteration in the voice is frequently the first observable indication of the malady, and should at once attract attention. In dumb madness the voice is frequently lost from the very commencement, -hence the designation. The sensibility of the mad dog appears to be considerably diminished, and the animal appears to have lost the faculty of expressing the sensations it experiences: it is mute under the infliction of pain, though there can be no doubt that it still has peripheral sensation to some extent. Burning, beating, and wounding produce much less effect than in health, and the animal will even mutilate itself with its teeth. Suspicion, therefore, should always strongly attach to a dog which does not manifest a certain susceptibility to painful impressions and receives punishment without any cry or complaint. There is also reason for apprehension when a dog bites itself persistently in any part of its body. A rabid dog is usually stirred to fury at the sight of one of its own species; this test has been resorted to by Bouley to dissipate doubts as to the existence of the disease when the diagnosis is otherwise uncertain. As soon as the suspected animal, if it is really rabid, finds itself in the presence of another of its species it at once assumes the aggressive, and, if allowed, will bite furiously. All rabid animals indeed become excited, exasperated, and furious at the sight of a dog, and attack it with their natural weapons, even the timid sheep when rabid butts furiously at the enemy before which in health it would have fled in terror. This inversion of sentiment is sometimes valuable in diagnosing the malady; it is so common that it may be said to be present in every case of rabies. When, therefore, a dog, contrary to its habits and natural inclination, becomes suddenly aggressive to other dogs, it is time to take precautions. a In the large majority of instances the dog is inoffensive in the early period of the disease to those to whom it is familiar. It then flies from its home and either dies, is killed as "mad," or returns in miserable plight, and in an advanced stage of the malady, when the desire to bite is irresistible. It is in the early stage that sequestration and suppressive measures are most valuable. The dogs which propagate the disease are usually those that have escaped from their owners. After two or three days, frequently in about twelve hours, more serious and alarming symptoms appear, ferocious instincts are developed, and the desire to do injury is irrepressible. The animal has an indefinable expression of sombre melancholy and cruelty. The eyes have their pupils dilated, and emit flashes of light when they are not dull and heavy; they always appear so fierce as to produce terror in the beholder; they are red and their sensibility to light is increased; and wrinkles, which sometimes appear on the forehead, add to the repulsive aspect of the animal If caged it flies at the spectator, emitting its characteristic howl or bark, and seizing the iron bars with its teeth, and if a stick be thrust before it this is grasped and gnawed. This fury is soon succeeded by lassitude, when the animal remains insensible to every excitement. Then all at once it rouses up again, and another paroxysm of fury commences. The first paroxysm is usually the most intense, and the fits vary in duration from some hours to a day, and even longer; they are ordinarily briefer in trained and pet dogs than in those which are less domesticated, but in all the remission is so complete after the first paroxysm that the animals appear to be almost well, if not in perfect health. During the paroxysms respiration is hurried and laboured, but tranquil during the remissions. There is an increase of temperature and the pulse is quick and hard. When the animal is kept in a dark place and not excited, the fits of fury are not observed. Sometimes it is agitated and restless in the manner already described. It never becomes really furious or aggressive unless excited by external objects, the most potent of these, as has been said, being another dog, which, however, if it be admitted to its cage, it may not at once attack. The attacked animal rarely retaliates, but usually responds to the bites by acute yells, which contrast strangely with the silent anger of the aggressor, and tries to hide its head with its paws or beneath the straw. These repeated paroxysms hurry the course of the disease. The secretion and flowing of a large quantity of saliva from the mouth are usually only witnessed in cases in which swallowing has become impossible, the mouth being generally dry. At times the tongue, nose, and whole head appear swollen. Other dogs frequently shun one which is rabid, as if aware of their danger. parts a curious and very characteristic physiognomy to the dog; the voice is also lost, and the animal can neither eat nor drink. In this condition the creature remains with its jaw pendent and the mouth consequently wide open, showing the flaccid or swollen tongue covered with brownish matter, and a stringy gelatinouslooking saliva lying between it and the lower lip and coating the fauces, which sometimes appear to be inflamed. Though the animal is unable to swallow fluids, the desire to drink is nevertheless intense; for the creature will thrust its face into the vessel of water in futile attempts to obtain relief, even until the approach of death. Water may be poured down its throat without inducing a paroxysm. The general physiognomy and demeanour of the poor creature inspire the beholder with pity rather than fear. The symptoms due to cerebral excitement are less marked than in the furious form of the disease; the agitation is not so considerable, and the restlessness, tendency to run away, and desire to bite are nearly absent; generally the animal is quite passive. Not unfrequently one or both eyes squint, and it is only when very much excited that the dog may contrive to close its mouth. Sometimes there is swelling about the pharynx and the neck; when the tongue shares in this complication it hangs out of the mouth. In certain cases there is a catarrhal condition of the membrane lining the nasal cavities, larynx, and bronchi; sometimes the animal testifies to the existence of abdominal pain, and the fæces are then soft or fluid. The other symptoms-such as the rapid exhaustion and emaciation, paralysis of the posterior limbs towards the termination of the disease, as well as the rapidity with which it runs its course are the same as in the furious form. The rabid dog, if lodged in a room or kept in a house, is continually endeavouring to escape; and when it makes its escape it goes freely forward, as if impelled by some irresistible force. It travels considerable distances in a short time, perhaps attacking every living creature it meets,-preferring dogs, however, to other animals, and these to mankind; cats, sheep, cattle, and horses are particularly liable to be injured. It attacks in silence, and never utters a snarl or a cry of anger; should it chance to be hurt in return it emits no cry or howl of pain. The degree of ferocity appears to be related to natural disposition and training. Some dogs, for instance, will only snap or give a slight bite in passing, while others will bite furiously, tearing the objects presented to them, or which they meet in their way, and sometimes with such violence as to injure their mouth and break their teeth, or even their jaws. If chained, they will in some cases gnaw the chain until their teeth are worn away and the bones laid bare. The rabid dog does not continue its progress very long. Exhausted by fatigue and the paroxysms of madness excited in it by the objects it meets, as well as by hunger, thirst, and also, no doubt, by the malady, its limbs soon become feeble; the rate of travelling is lessened and the walk is unsteady, while its drooping tail, head inclined towards the ground, open mouth, and protruded tonguo (of a leaden colour or covered with dust) give the distressed creature a very striking and characteristic physiognomy. In this condition, however, it is much less to be dreaded than in its early fits of fury, since it is no longer capable or desirous of altering its course or going out of its way to attack an animal or a man not immediately in the path. It is very probable that its fast-failing vision, deadened scent, and generally diminished perception prevent its being so readily impressed or excited by surrounding objects as it previously was. To each paroxysm, which is always of short duration, there succeeds a degree of exhaustion as great as the fits have been violent and oft repeated. This compels the animal to stop; then it shelters itself in obscure places-frequently in ditches by the roadside-and lies there in a somnolescent state for perhaps hours. There is great danger, nevertheless, in disturbing the dog at this period; for when roused from its torpor it has sometimes sufficient strength to inflict a bite. This period, which may be termed the second stage, is as variable in its duration as the first, but it rarely exceeds three or four days. The above-described phenomena gradually merge into those of the third or last period, when symptoms of paralysis appear, which are speedily followed by death. During the remission in the paroxysms these paralytic symptoms are more particularly manifested in the hind limbs, which appear as if unable to support the animal's weight, and cause it to stagger about; or the lower jaw becomes more or less drooping, leaving the parched mouth partially open. Emaciation rapidly sets in, and the paroxysms diminish in intensity, while the remissions become less marked. The physiognomy assumes a still more sinister and repulsive aspect; the hair is dull and erect; the flanks are retracted; the eyes lose their lustre and are buried in the orbits, the pupil being dilated, and the cornea dull and semi-opaque; very often, even at an early period, the eyes squint, and this adds still more to the terrifying appearance of the poor dog. The voice, if at all heard, is husky, the breathing laborious, and the pulse hurried and irregular. Gradually the paralysis increases, and the posterior extremities are dragged as if the animal's back were broken, until at length it becomes general; it is then the prelude to death. Or the dog remains lying in a state of stupor, and can only raise itself with difficulty on the fore-limbs when greatly excited. In this condition it may yet endeavour to bite at objects within its reach. At times convulsions of a tetanic character appear in certain muscles; at other times these are general. A comatose condition ensues, and the rabid dog, if permitted to die naturally, perishes, in the great majority of cases, from paralysis and asphyxia. In dumb madness there is paralysis of the lower jaw, which im. The simultaneous occurrence of furious and dumb madness is frequently observed in packs of fox-hounds. Dumb madness differs, then, from the furious type in the paralysis of the lower jaw, which hinders the dog from biting, save in very exceptional circumstances; the ferocious instincts are also in abeyance; and there is no tendency to aggression. It has been calculated that from 15 to 20 per cent. of rabid dogs have this particular form of the disease. Puppies and young dogs chiefly have furious rabies. These are the symptoms of rabies in the dog; but it is not likely, nor is it necessary, that they will all be present in every case. In other species the symptoms differ more or less from those manifested by the dog, but they are generally marked by a change in the manner and habits of the creatures affected, with strong indications of nervous disturbance, in the majority of species amounting to ferociousness and a desire to injure, timid creatures becoming bold and aggressive. (See Fleming, Rabies and Hydrophobia.) In order to prevent injury from this disease in countries in which it is prevalent owners of dogs should be well acquainted with its symptoms, especially the premonitory ones; of these a change in the demeanour and habits of the animal-unusual irritability, depraved appetite, restlessness, and a tendency to wander from home-are the most marked. One of the chief police measures is diminution in the number of useless dogs. This is best enforced by the imposition of a dog-tax or licence, which may be large or small in proportion to the number of dogs or the urgency of the case. On the licence-paper the chief symptoms of the malady should be described so as to warn dog-owners. Every dog should wear a collar with a brass plate, on which are inscribed the name and address of the owner as well as a police register-number stamped thereon, or some particular mark affixed by the police or inland revenue authorities, for purposes of identification; all stray dogs without a collar of this description ought to be captured, and sold or destroyed after three or more days if not claimed. Blunting the canine and incisor teeth of dogs has also been proposed as a precautionary measure. All dogs suspected of rabies should be captured and, when the existence of the disease is confirmed, destroyed. Rabid dogs should be destroyed at once. also well as a precautionary measure to kill dogs or cats which have been bitten or worried" by rabid animals. During an outbreak of rabies all dogs should be securely muzzled and if possible led. It is a great mistake to destroy immediately suspected dogs which have bitten people; they should be kept until their condition is ascertained, as, if they are found to be healthy, this will greatly relieve should be carefully kept under observation and frequently the mind of those who have been bitten. Suspected dogs inspected by a veterinary surgeon or other competent per XX. It is son. All wounds inflicted by strange or suspected dogs | Rouville. When the Fronde broke out he, like others, went We may here allude to the results of Pasteur's experi- Although a man of considerable abilities, Bussy had very little The Histoire Amoureuse is in its most The best edition of the Histoire Amoureuse des Gaules is that of Boiteau and RACCOON. This name, familiar to all readers of ( range extends over the whole of the United States, and | stretches on the west northwards to Alaska and southwards Raccoon. well into Central America, where it attains its maximum It does little in the way of constructing a nest, and from four to six young are commonly born at a time, generally carly in April in this region. The young remain with the mother about a year." The South-American species, Procyon cancrivorus, the crab-eating raccoon, is very similar to P. lotor, but differs by its much shorter fur, larger size, proportionally more powerful teeth, and other minor characters. It extends over the whole of South America, as far south as the Rio Negro, and is very common in all suitable localities. Its habits are similar to those of the North-American species. Sophia gained a medal for singing, but Rachel at an early RACHEL (1820 or 1821-1858), the stage name of a RACINE, a city of the United States, the county seat of Racine county, Wisconsin, lies 23 miles by rail south of Milwaukee, and occupies a plateau projecting for about 6 miles into Lake Michigan, 40 feet above its level. The town is the seat of extensive manufacturing industriesproducing carriages, waggons, ploughs, threshing-machines, portable steam-engines, fanning-mills, leather, blinds and sashes, school furniture, wire, linseed oil, baskets, &c.is engaged in the lumber trade and general commerce, and contains two city hospitals, an orphan asylum, Racine (Episcopalian) college founded in 1852, and a Roman Catholic academy. The harbour is open to vessels drawing 15 feet. Racine, first settled in 1834, was incorporated in 1848, four years after the first steamer had entered the port. The population was 7822 in 1860, 9880 in 1870, and 16,031 in 1880. |