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must be gently purged, three or four times, as the case may require.

The next object we meet with in the historical part of this volume, is the meteorological correspondence of the Society, accompanied with twenty-fix large tables, which contain the observations of F. Corte relative to the temperature of the air, the variations of the barometer and thermometer, the heat and cold, the winds and weather, and the reigning diseases in 1780 and 1781. The temperature of the year in 1780 was the same with that which was observed in the correspondent years of the lunar period of 19 years, viz. 1704, 1723, 1742, and 1761. The weather in 1781 was extremely warm and dry; all the productions of the earth were premature, and crops of every kind were rich and abundant. The same temperature and the same fecundity were observed in 1705, 1724, 1743, and 1762, the years of the lunar period of 19 years, which correspond to the year 1781. The influence of the smaller periods indicated by M. Toaldo were not confirmed by the observations of Father COTTE.

Of the remaining observations that are contained in the historical class, those that relate to medical practice are

Observations on an Aperture in the stomach. By M. GeorFROY.-On a remarkable Alteration in the Colour of the skin. By • M. de CHAMSERU. This is an icterical disease, of a new spe.

cies, in which the body of a female child, eight years old, was covered with a dark, blackish, violet colour, accompanied with other disagreeable symptoms. It was supposed to proceed from a thick, viscous, fuperabundant blood, and a languid circulation. Some accidental circumstances prevenced the physician from pur-' suing the treatment which the disease seemed to require. In a similar case, by attenuating the blood and augmenting the action of the fibres, the juice of antiscorbutic plants gave considerable relief to the patient; but we have no account of a complete cure.

On a Caries which was occafioned (as appears) by a sudden Impression made by a Current of Air on a Person who was heated and almost exhaufied by hard Labour. By Messrs. VARNIER and LAGUERENE.

On the Dissections of two Bodies which exhibited Phenomena totally different from those which the Diseases seemed to indicate. By M. Hable. One was a schirrous induration of the membranes of the stomach; the other, a singular alteration of the natural state of the kidneys.

A Series of Observations made by M. Vice D'Azyr on differe ent kinds of animal Concretions ; and on other Subjects. By the Same.

On a Man who had a monthly Flux of Blood, which issued from the End of the little Finger of his right Hand. By M. CARRERE. This Gngular Aux was always preceded by a head-ach, which

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ceased when the evacuation was finished. When attempts were made to suppress this evacuation, the suspension occasioned diso orders in other parts of the body, such as peripneumonies, dyfenteries, and spitting of blood, which complaints ceased when tbe evacuation was restored *.

The materia medica and medical chemistry have also furnished several articles for the historical part of the volume before us; such as

Observations and Experiments on the Saliva, or Spittle of Horses. By M. H. DE LA CHENAIE, Professor in the Veterinarian School at Paris. The nature of the saliva considered in general

-the chemical and physical properties of the pure faliva of the horse-the manner in which it is affected by different degrees of hear in open or closed vessels--the action of water and saline matters on pure saliva---and the examination of the saliva taken from the mouth of the horse, and mixed with the other Auids of that cavity-all these points are here treated with brevity, skill, and attention.

REPORT of the Memoir composed by Dr. Jofeph Flores, mem.' ber of the Univerlity of Guatimala in New Spain, which contains an account of a specific lately discovered in the Kingdom of Guatimala for the Cure of the Cancer, and some other Di; orders frequent in that country. This method of cure confiits in making : The patient eat, during three days or longer, if the virulence and obftinacy of the cancer require it, a kind of lizard, which is common in the province of Guatimala, and which the inhabit. ants call lagartija. The Indians, as we learn from the Spanish memoir t, cut off the head and the tail of this replile, and hav. ing separated from it the entrails and the skin, eat it raw, and even with some feeble remains of life. This method of employ. ing the remedy being impracticable in Europe, it would, pero haps, be worth the pains of an inventive practitioner to contrive such a preparation of the substance of this reprile, as might be transportable, in pills or boluffes, into our parts of The world, but to make, previously, a trial of the efficacy of such a preparation on a certain number of patients in the province of Guatimala. The Society obtained from Spain, by the good offices of Count de Vergennes, a certain number of the lizards of Guatimala, and also of those which are found in Spain, which seem to differ little, if at all, from the American lizards. Messieurs D'Aubenton and Mauduyt have been appointed by the

* This is not a iew or unknown case. See Lowthorp's Abridge ment of the Philosophical Transactions, vol. iii. p. 248.-the case of Walter Wash from the finger, and similar periodical evacuations from other parts of the body.

Published at Guatimala, and republished at Madrid in 4to in the year 1782.

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Society, to make trial of their respective virtues in cancerous and cutaneous diseases, and also to comprehend in their experiments the French ). Zards, which seem to differ little fiom those of Spain. The cases of persons cured of the most virulent and inveterate cancers by these reptiles in the province of Guaria mala, are circumstantially described by M. CARRERE, the Au. thor of this report. They are very remarkable, and render fur. ther inquiries into this matter highly desirable, as they may terminate in discoveries of great confequence to medical science and to humanity. The manner in which this remedy operates seems to confirm strongly the accounts which have been given of its efficacy. It promotes evacuations, more especially abun. dant sweating, and a confiderable falivation, which discharges a thick yellowish matter. Where these evacuations do not take place, the want of them is compensated by an ample excretion of acrimonious and foetid urine, which contributes equally to the relief of the patient.

A Letter from the Chevalier d'ARBALESTRIER, dated February 14, 1781, menrions the lobelia fyphilitica, a plant which grows in Canada (and which was sent to him from thence), as a moft efficacious remedy for the venereal disease. In his botanical excursions on the Alps, he found a plant, fimiJar in its appearance to that now mentioned, called phyteuma, with a decoction of which he radically cured several foldiers, who were in the moft advanced stage of that abominable disease. This plant is also remarkable for its efficacy in the cure of niany chronical disorders, occafioned by a vitiated lymph.

On the deadly Effects of a Mushroom, which may be denomi. naved Agaricus Conicus. By M. Picco, corresponding Member ac Turin. We have here an account of fix persons who were poisoned by this mushroom, of which the Author gives a parcia cular description, accompanied with drawings. Four of them died in consequence of their refusal of the remedies that were offered: the other two were restored to health. The symptoms of the disorder are here circumftantially described; the cure is performed by emerics; for vomiting, excited without loss of time, is, according to our Author, 'the principal relief against the corrofive and foporific poison of mushrooms, when followed by the use of softening and mucilaginous substances to correct the im.. preffion made on the prime vie, and prevent inflammation, which, in such cases, generally terminates in a gangrene.

We find a remarkable poltscripe annexed to this narration, which is as follows: I have received a letter from M. J. Reycends, dated the 29th of last Auguft. He tells me, that he learned from M. ENOCH, fuperior of the O atory in the lemia nary of Grenoble, that a family at Ghent, which had ben poisoned by mushrooms, were cured by an infufion of pear-tree Mm 4


leaves, drank as tea, after having ineffe&tually tried several other remedies. This reminds me of the great confidence that was placed in the leaves of the wild pear-tree by the ancients, who recommended it to those who had suffered by eating muhi. rooms,

Experiments relative to the Influence of the different Plants and Grains upon the qualities of the Bread used by Peasants and Farmers (in France). By the Abbé TESSIER. Though these experiments relate to the plants that grow among corn, and some kinds of grain that are mixed with it in the barn, in a particular diftrict (La Beauce), yet something analogous to this mixture may be found in other places and other countries; and therefore the experiments may prove more generally useful than they seem to be, at first fight. The Society has been often consuleed on the epidemics, which have been supposed to arise from these heterogeneous mixtures. The grain or plants wbịch, in the district of Beauce, were found among wheat, rye, barley, and oats, were the hare-bell or grape flowers; the cow-wheat ; the darnel ; the ray or rye grass ; tares, or vetches ; also the Imut or blight, which, though mentioned as a grain, is rather a disease of the corn. The Abbé Tessier describes concisely, yer with remarkable perspicuity and precision, these plants and their seeds. He has mixed their flours with one another in dif. ferent ways, sometimes taking each alone, and sometimes adding to each some leaven and the flour of good corn in certain proportions. These experiments have enabled him to indicate the marks which ascertain the existence and proportion of each grain in the bread of the poorer part of the community, who are fed with the remains of the fieve, or with what is left on the threshing floor, and in the granary, when the best part of the corn is separated from it.

The historical part of this volume is terminated by an ample table of the specific weight of several substances employed in medical practice, and by observations on the number of births, marriages, and deaths at Montpellier during the space of ten years; that is, from 1772 till 1782 inclusive,

MEMOIRS. Mem. I. Concerning the Temperature of the Years 1780 and 1781, with an Account of the Diseases that reigned at Paris during these two Years. By M. GEOFFROY. We have here a precise account of the ftate of the air, in each season, in each month, and its influence in producing diseases, whose symptoms and treatment are largely described in this interesting and inAructive memoir.

Mem. II. Concerning Epidemics. By M. RAIMOND, M. D, In this memoir, remarkably for its solidity, precision, and perSpicuity, the learned Member discusses the following important



question: What connexion is there between epidemical diseases and other disorders which happen in the same place, and ai the same time, and are called intercurrent and intervening ? What are the complications that take place between them, and what influence ought these complications to have on the method of treating themThis was proposed by the Society as a prize question, and as the pieces given in did not prove entirely satisfactory, the question was proposed a second time with a double premium, which was obtained by the Author of this memoir. An epidemic dysen. tery in the southern provinces of France in the years 1779 and 1780, was the occasion of this question. In the first part of this memoir the Author endeavours to ascertain the connections and relations that subsist between epidemical and intercurrent diseases, by their evident occasional causes, and by their symptoms. The former are the general properties of the air, which result from the nature of the weather, the state of the seasons, and the conftitution of the years, i.e. the permanence or continuance of a certain temperature (such as dry beat, humid cold, dry cold, or humid heat), during one or more years. The nature and characters of the latter are enumerated, in an interesting analysis of a great variety of epidemical and intercurrent diseases, which (as the Author concludes from this analysis) are derived from the same causes. The method of cure, founded in these ob. servations, is the subject of the second part.

Mem. III. A medical Account of the Constitution or Temperature of the Year 1778, together with a History of the epidemic Dysentery that reigned during the Year 1779, in the Town of Pommeraie sur Sevre, in the Lower Poitou. By M. DURAND.. This piece, on the same subject with the preceding article, met with a favourable reception from the Society.

Mem. IV. Concerning the Topography of the Town St. Andeol, medically considered. By M. MADIER, Correspondent of the Society. This memoir, though but locally interesting, may, however, be of more extenlive utility, considered as a model worthy the imitation of those who examine the situation of places as conducive or detrimental to the health of their inhabitants.

Mem. V. A Differtation on the following Question : Does there really exist a miliary Fever, essential in its Principle, and distinct from other exanthematous Fevers ? and if so, in what Habit of Body is it most to be expected ? By M. AUFAVRE, correspond- : ing Member. In order to proceed methodically in the examination of this question, the Author sets out by giving a history of the miliary fever, which contains an accurate delcription of that disease; he indicates the symptoms which precede and accompany it, and points out the different ways in wbich it terminates. He, afterward, mentions the persons, considered



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